Treating Depression in African American Children: A Decision Tree Case Study

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ASSIGNMENT INSTRUCTION:

An African American Child Suffering from Depression
Decision Tree Case Study: Therapy for pediatric clients with mood disorders Links to an external site.[Interactive media file].
Write a 1-2 page narrative in APA format that addresses the following:
Compare and state why you chose the medications in decision 1,2,3 briefly.
a) Explain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples.
b) Describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
Reference to include:-
· Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.
o Chapter 9, “Drug Therapy in Pediatric Patients” (pp. 58—60)
· Panther, S. G., Knotts, A. M., Odom-Maryon, T., Daratha, K., Woo, T., & Klein, T. A. (2017). Off-label prescribing trends for ADHD medications in very young children Links to an external site.. The Journal of Pediatric Pharmacology and Therapeutics, 22(6), 423–429. doi:10.5863/1551-6776-22.6.423

HOW TO WORK ON THIS ASSIGNMENT ( EXAMPLE ESSAY/ DRAFT)

Introduction: Depression is a mental health condition that can affect children and adolescents, leading to significant distress and interference in their daily activities. The use of medications for depression in pediatric populations is a complex and controversial issue, requiring careful consideration of the risks and benefits. This narrative aims to compare the medications in decision 1, 2, and 3 and provide an overview of the circumstances under which children should be prescribed drugs for off-label use.

Section 1: Comparison of Medications in Decision 1, 2, and 3 The medications in decision 1, 2, and 3 are commonly used to treat depression in pediatric populations. However, each medication has different mechanisms of action, side effect profiles, and clinical indications.

Decision 1: Selective Serotonin Reuptake Inhibitors (SSRIs) SSRIs are the most commonly prescribed class of antidepressants for children and adolescents. They work by increasing the levels of serotonin in the brain, which regulates mood, sleep, and appetite. SSRIs have a relatively low risk of adverse effects and are well-tolerated in pediatric populations.

Decision 2: Tricyclic Antidepressants (TCAs) TCAs are an older class of antidepressants that have been used in pediatric populations for decades. They work by blocking the reuptake of serotonin and norepinephrine, leading to increased levels of these neurotransmitters in the brain. TCAs have a higher risk of adverse effects, including anticholinergic effects, cardiovascular effects, and overdose, and are typically used as a second-line treatment option in pediatric populations.

Decision 3: Atypical Antidepressants Atypical antidepressants are a newer class of antidepressants that have a different mechanism of action compared to SSRIs and TCAs. They work by blocking the reuptake of serotonin, norepinephrine, and dopamine. Atypical antidepressants have a lower risk of adverse effects compared to TCAs, but have a more complex side effect profile compared to SSRIs.

Section 2: Circumstances for Off-Label Use of Medications in Pediatrics Off-label use of medications in pediatrics refers to the use of a medication for a condition that is not approved by the regulatory body. In some cases, the use of a medication off-label may be justified based on clinical evidence and the benefits outweigh the risks.

Examples of circumstances where off-label use of medications may be justified in pediatrics include:

  • Lack of FDA-approved medications for a particular condition
  • The medication has shown efficacy in treating similar conditions
  • The medication has a favorable safety profile compared to other available options
  • The medication is the only option for a life-threatening condition

Section 3: Strategies for Safe Off-Label Use in Pediatrics To ensure the safe off-label use of medications in pediatric populations, several strategies can be employed, including:

  • Careful monitoring of the child’s response to the medication
  • Close monitoring of the child’s vital signs and adverse effects
  • Regular reassessment of the need for the medication
  • Adjustment of the dosage based on the child’s weight and age

Off-label drugs that require extra care and attention when used in pediatrics include:

  • Stimulants for Attention Deficit Hyperactivity Disorder (ADHD)
  • Antipsychotics for behavioral and mood disorders
  • Anticonvulsants for mood and behavioral disorders

Conclusion: The use of medications for depression in pediatric populations is a complex and controversial issue that requires careful consideration of the risks.

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